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51 results for "Integrin alpha 4 beta 1" in Products

Integrin alpha 4 beta 1 Products

Integrin alpha 4 beta 1, also known as VLA-4, is an Integrin family adhesion receptor that shares the beta 1 subunit with eleven other family members and the alpha 4 subunit with Integrin alpha 4 beta 7. The noncovalent heterodimer of alpha 4/CD49d and beta 1/CD29 subunits mediates cell adhesion to VCAM-1/CD106 on other cells and the CS-1 fragment of Fibronectin in the extracellular matrix. Leukocytes (except for neutrophils), erythroid precursors, and some non-hematopoietic cells such as ...

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Reactivity:
Human
Source:
CHO
Accession #:
P13612 (Integrin alpha 4) & P05556 (Integrin beta 1)
Applications:
Bioactivity
R&D Systems Recombinant Proteins and Enzymes

Recombinant Monoclonal Antibody For Research Use Only

Reactivity:
Human
Details:
Human IgG4 Monoclonal Clone #Hu114
Applications:
Flow, CyTOF-ready
(2)

Selective α4β1 (VLA-4) inhibitor

Purity:
≥95%
Selective α4β1 (VLA-4) inhibitor
Reactivity:
Mouse
Source:
CHO
Accession #:
AAH68313 (Integrin alpha 4) & P09055 (Integrin beta 1)
Applications:
Bioactivity
R&D Systems Recombinant Proteins and Enzymes

Fc Chimera

Reactivity:
Human
Source:
HEK293
Applications:
Bioactivity
(2)

Fluorescent ligand for α4β1 (VLA-4)

Purity:
≥90%
Fluorescent ligand for α4β1 (VLA-4)

Highly potent and selective inhibitor of integrin α4β1 (VLA-4)

Chemical Name:
(2S)-2-[[[(2S)-1-[(3,5-Dichlorophenyl)sulfonyl]-2-pyrrolidinyl]carbonyl]amino]-4-[[(2S)-4-methyl-2-[methyl[2-[4-[[[(2-methylphenyl)amino]carbonyl]amino]phenyl]acetyl]amino]-1-oxopentyl]amino]butanoic acid
Purity:
≥98%
Highly potent and selective inhibitor of integrin α4β1 (VLA-4)

Fc Chimera

Reactivity:
Human
Source:
HEK293
Applications:
Bioactivity
(2)

Highly potent and selective inhibitor of integrin α4β1 (VLA-4)

Chemical Name:
(2S)-2-[[[(2S)-1-[(3,5-Dichlorophenyl)sulfonyl]-2-pyrrolidinyl]carbonyl]amino]-4-[[(2S)-4-methyl-2-[methyl[2-[4-[[[(2-methylphenyl)amino]carbonyl]amino]phenyl]acetyl]amino]-1-oxopentyl]amino]butanoic acid
Purity:
≥98%
Highly potent and selective inhibitor of integrin α4β1 (VLA-4)

Potent integrin α4β7 and α4β1 (VLA-4) antagonist; orally bioavailable

Chemical Name:
(αS)-α-[(2,6-Dichlorobenzoyl)amino]-2',6'-dimethoxy[1,1'-biphenyl]-4-propanoic acid
Purity:
≥98%
Potent integrin α4β7 and α4β1 (VLA-4) antagonist; orally bioavailable

α4β1 (VLA-4) ligand

Purity:
≥95%
α4β1 (VLA-4) ligand

Recombinant Monoclonal Antibody.

Reactivity:
Human
Details:
Human IgG1 Monoclonal Clone #Hu114
Applications:
Flow
Human Integrin  alpha 4 beta 1 (Research Grade Natalizumab Biosimilar) Alexa Fluor® 488‑conjugated Antibody
(2)

Recombinant Monoclonal Antibody.

Reactivity:
Human
Details:
Human IgG1 Monoclonal Clone #Hu114
Applications:
Flow
(2)

Recombinant Monoclonal Antibody.

Reactivity:
Human
Details:
Human IgG1 Monoclonal Clone #Hu114
Applications:
Flow
Human Integrin  alpha 4 beta 1 (Research Grade Natalizumab Biosimilar) Alexa Fluor® 700‑conjugated Antibody

Recombinant Monoclonal Antibody.

Reactivity:
Human
Details:
Human IgG1 Monoclonal Clone #Hu114
Applications:
Flow
Human Integrin  alpha 4 beta 1 (Research Grade Natalizumab Biosimilar) Alexa Fluor® 750‑conjugated Antibody

Recombinant Monoclonal Antibody.

Reactivity:
Human
Details:
Human IgG1 Monoclonal Clone #Hu114
Applications:
Flow
Human Integrin  alpha 4 beta 1 (Research Grade Natalizumab Biosimilar) Alexa Fluor® 594‑conjugated Antibody

Recombinant Monoclonal Antibody.

Reactivity:
Human
Details:
Human IgG1 Monoclonal Clone #Hu114
Applications:
Flow
Human Integrin  alpha 4 beta 1 (Research Grade Natalizumab Biosimilar) Alexa Fluor® 350‑conjugated Antibody

Recombinant Monoclonal Antibody.

Reactivity:
Human
Details:
Human IgG1 Monoclonal Clone #Hu114
Applications:
Flow
Human Integrin  alpha 4 beta 1 (Research Grade Natalizumab Biosimilar) Alexa Fluor® 405‑conjugated Antibody
Reactivity:
Human
Details:
Human IgG4 Monoclonal Clone #Hu114
Applications:
Flow, CyTOF-ready
Reactivity:
Human
Details:
Human IgG4 Monoclonal Clone #Hu114
Applications:
Flow, CyTOF-ready
Reactivity:
Human
Details:
Human IgG4 Monoclonal Clone #Hu114
Applications:
Flow, CyTOF-ready
Reactivity:
Human
Details:
Human IgG4 Monoclonal Clone #Hu114
Applications:
Flow, CyTOF-ready
Reactivity:
Human
Details:
Human IgG4 Monoclonal Clone #Hu114
Applications:
Flow, CyTOF-ready
Reactivity:
Human
Details:
Human IgG4 Monoclonal Clone #Hu114
Applications:
Flow, CyTOF-ready
Reactivity:
Human
Details:
Human IgG4 Monoclonal Clone #Hu114
Applications:
Flow, CyTOF-ready
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