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93 results for "Insulysin/IDE" in Products

Insulysin/IDE Products

Insulysin, or insulin-degrading enzyme (IDE), is a zinc metallopeptidase of the inverzincin family. IDE is primarily located in the cytosol, but has been detected as a secreted enzyme and associated with the plasma membrane as well. The enzyme is expressed in many tissues, with the highest levels in liver, kidney, brain, and testis. IDE hydrolyzes a variety of regulatory peptides, including insulin, glucagon, atrial natriuretic factor, and transforming growth factor-alpha in vitro. In addition, IDE has been shown to degrade the amyloid beta (A beta) peptide, which polymerizes into the plaques associated with Alzheimer's disease.

Source: Sf 21 (baculovirus)
Accession #: P14735
Applications: EnzAct
R&D Systems Recombinant Proteins and Enzymes
Reactivity: Human, Mouse, Rat
Details: Mouse IgG2B Monoclonal Clone #GT143
Applications: IHC, WB
Western Blot: Insulysin/IDE Antibody (GT143) [NBP3-13560]
(5)
Reactivity: Human, Mouse, Rat
Details: Mouse IgG1 Monoclonal Clone #GT286
Applications: IHC, WB
Western Blot: Insulysin/IDE Antibody (GT286) [NBP3-13547]
(4)
Source: Sf 21 (baculovirus)
Accession #: P35559
Applications: EnzAct
R&D Systems Recombinant Proteins and Enzymes
Reactivity: Human
Details: Goat IgG Polyclonal
Applications: IHC, WB, ELISA
Western Blot: Insulysin/IDE Antibody [NB100-68148]
(3)
Reactivity: Human, Mouse
Details: Rabbit IgG Polyclonal
Applications: WB, ICC/IF, KO
Western Blot: Insulysin/IDE AntibodyBSA Free [NBP3-03392]
(4)
Applications: AC
Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #334501
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