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IFN-beta Products

IFN-beta (Interferon-beta) is a cytokine that is produced by fibroblasts and pathogen-exposed dendritic cells, macrophages, and endothelial cells. It signals through the heterodimeric IFN-alpha/beta Receptor. IFN-beta-deficient mice show increased susceptibility to experimental autoimmune encephalomyelitis (EAE), a disease model of human multiple sclerosis (MS). Furthermore, IFN-beta has been shown to suppress the Th17 cell response in both MS and EAE and has commonly been used as a treatment for MS.

Toll-like receptor 7 (TLR7) agonist

Alternate Names:
R 837
Chemical Name:
1-(2-Methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine
Purity:
≥98%
Toll-like receptor 7 (TLR7) agonist
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