HNF-4 alpha/NR2A1 Products
Hepatocyte Nuclear Factor 4 alpha (HNF4 alpha; NR2A1) is a member of the orphan nuclear receptor family. HNF4 alpha is expressed in the liver, kidney, intestine and pancreas. Mutation of HNF4 alpha in humans has been associated with maturity-onset diabetes of the young type 1 (MODY1). HNF4 binds to DNA as an exclusive homodimer. The HNF4 alpha gene is alternatively spliced and may generate up to nine different isoforms, HNF4 alpha 1 through HNF4 alpha 9. The expression of HNF-4 gamma (NR2A2) is observed in the pancreas, kidney, small intestine, and testes with no expression detected in the liver. The level of HNF-4 gamma is less 10% than that of HNF-4 alpha.
13 results for "HNF-4 alpha/NR2A1" in Products
Search
Application
Conjugates
Clonality
Host Species
Isotype
Clone
Low Endotoxin
Sample Size
Citations
Reviews
HNF-4 alpha/NR2A1 Products
Hepatocyte Nuclear Factor 4 alpha (HNF4 alpha; NR2A1) is a member of the orphan nuclear receptor family. HNF4 alpha is expressed in the liver, kidney, intestine and pancreas. Mutation of HNF4 alpha in humans has been associated with maturity-onset diabetes of the young type 1 (MODY1). HNF4 binds to DNA as an exclusive homodimer. The HNF4 alpha gene is alternatively spliced and may generate up to nine different isoforms, HNF4 alpha 1 through HNF4 alpha 9. The expression of HNF-4 gamma (NR2A2) is observed in the pancreas, kidney, small intestine, and testes with no expression detected in the liver. The level of HNF-4 gamma is less 10% than that of HNF-4 alpha.
13 results for "HNF-4 alpha/NR2A1" in Products
Clonality : | Monoclonal |
Host : | Mouse IgG2b Clone #843716 |
Applications : | Flow Cytometry, Immunocytochemistry/Immunofluorescence, Simple Western, Western Blot |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Simple Western, Western Blot |
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #H1415 |
Applications : | Chromatin Immunoprecipitation, ELISA, Gel Shift, Immunohistochemistry, Immunoprecipitation, Western Blot |
Hepatocyte nuclear factor 4α (HNF4α) antagonist
Chemical Name : | 2-Methyl-1-[(2-methyl-5-nitrophenyl)sulfonyl]-1H-benzimidazole |
Purity : | ≥98% (HPLC) |
Isoforms 7-9
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #H6939 |
Applications : | Immunohistochemistry, Immunoprecipitation, Western Blot |
Isoforms 1-6
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #K9218 |
Applications : | Immunohistochemistry, Immunoprecipitation, Western Blot |
Clonality : | Monoclonal |
Host : | Mouse IgG2b Clone #843716 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG2b Clone #843716 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG2b Clone #843716 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG2b Clone #843716 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG2b Clone #843716 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG2b Clone #843716 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG2b Clone #843716 |
Applications : | Flow Cytometry |