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Helios: Antibodies

Helios, also known as IKZF2, is a 70 kDa DNA-binding transcription regulator in the Ikaros family that contains four N-terminal C2H2-type zinc finger domains and two C-terminal zinc finger domains. Helios is expressed in developing hematopoietic and epithelial tissues and in adult T cells and thymic-derived regulatory T cells (Treg). It forms homodimers and also heterodimers with other Ikaros family proteins Ikaros, Pegasus, Eos, and Aiolos. Alternate splicing of human Helios generates a short isoform that lacks three of the the N-terminal zinc finger domains. This isoform is overexpressed in T cell leukemias where it can still dimerize with Ikaros proteins but functions as a dominant negative regulator.

82 results for "Helios Primary Antibodies" in Products

Helios: Antibodies

Helios, also known as IKZF2, is a 70 kDa DNA-binding transcription regulator in the Ikaros family that contains four N-terminal C2H2-type zinc finger domains and two C-terminal zinc finger domains. Helios is expressed in developing hematopoietic and epithelial tissues and in adult T cells and thymic-derived regulatory T cells (Treg). It forms homodimers and also heterodimers with other Ikaros family proteins Ikaros, Pegasus, Eos, and Aiolos. Alternate splicing of human Helios generates a short isoform that lacks three of the the N-terminal zinc finger domains. This isoform is overexpressed in T cell leukemias where it can still dimerize with Ikaros proteins but functions as a dominant negative regulator.

82 results for "Helios Primary Antibodies" in Products

WB, IHC
CyTOF-ready, ICFlow
WB, IP
Catalog #: IC73092T
ICFlow
Catalog #: IC73092G
ICFlow
Catalog #: IC73092R
ICFlow
Catalog #: IC73092U
ICFlow
Catalog #: IC73092N
ICFlow
Catalog #: IC73092V
ICFlow
Catalog #: IC73092S
ICFlow
IP, WB
IHC, WB
CyTOF-ready, Flow
Catalog #: FAB73092J
CyTOF-ready, Flow
IP, WB
Catalog #: FAB73092D
CyTOF-ready, Flow
IP, WB
CyTOF-ready, Flow
Catalog #: NBP2-04050C
IP, WB
CyTOF-ready, Flow
Catalog #: NBP2-04050FR
IP, WB
Catalog #: FAB73092E
CyTOF-ready, Flow
CyTOF-ready, Flow
IP, WB
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