Helios Products
Helios, also known as IKZF2, is a 70 kDa DNA-binding transcription regulator in the Ikaros family that contains four N-terminal C2H2-type zinc finger domains and two C-terminal zinc finger domains. Helios is expressed in developing hematopoietic and epithelial tissues and in adult T cells and thymic-derived regulatory T cells (Treg). It forms homodimers and also heterodimers with other Ikaros family proteins Ikaros, Pegasus, Eos, and Aiolos. Alternate splicing of human Helios generates a short isoform that lacks three of the the N-terminal zinc finger domains. This isoform is overexpressed in T cell leukemias where it can still dimerize with Ikaros proteins but functions as a dominant negative regulator.
158 results for "Helios" in Products
158 results for "Helios" in Products
Helios Products
Helios, also known as IKZF2, is a 70 kDa DNA-binding transcription regulator in the Ikaros family that contains four N-terminal C2H2-type zinc finger domains and two C-terminal zinc finger domains. Helios is expressed in developing hematopoietic and epithelial tissues and in adult T cells and thymic-derived regulatory T cells (Treg). It forms homodimers and also heterodimers with other Ikaros family proteins Ikaros, Pegasus, Eos, and Aiolos. Alternate splicing of human Helios generates a short isoform that lacks three of the the N-terminal zinc finger domains. This isoform is overexpressed in T cell leukemias where it can still dimerize with Ikaros proteins but functions as a dominant negative regulator.
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #736423 |
| Applications: | WB, IHC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #736440 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #736423 |
| Applications: | WB, IHC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #736440 |
| Applications: | CyTOF-ready, ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #736423 |
| Applications: | WB, IHC |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #736440 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #736440 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #736440 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #736440 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #736440 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #736440 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #736423 |
| Applications: | WB, IHC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #736423 |
| Applications: | WB, IHC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #736423 |
| Applications: | WB, IHC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #736423 |
| Applications: | WB, IHC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #736423 |
| Applications: | WB, IHC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #736423 |
| Applications: | WB, IHC |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, IP |