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14 results for "GSK-3 alpha/beta" in Products

GSK-3 alpha/beta Products

GSK-3 is a Ser/Thr kinase first identified as an inactivator of Glycogen Synthase. GSK-3 acts as a multifunctional downstream switch that determines the output of numerous signaling pathways. There are two mammalian GSK-3 isoforms encoded by distinct genes, GSK-3 alpha and GSK-3 beta, which are structurally similar, but functionally non-identical. GSK-3a is inhibited by phosphorylation at S21 by Akt and other kinases. GSK-3 alpha and GSK-3 beta share 85% amino acid identity. Dysregulated GSK-3 has been implicated in several diseases including type II diabetes, Alzheimer's disease, bipolar disorder, and cancer.

Contains 4 sets of 2 membranes - each spotted in duplicate with antibodies against 37 different kinases and 2 related total proteins

Reactivity:
Human
Detection of human protein kinase phosphorylation in A549 Cell Line.
(4)
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Polyclonal
Applications:
WB, ICC/IF
Detection of Human Phospho-GSK-3a (S21) and GSK-3 beta  (S9) antibody by Western Blot.
(8)
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Polyclonal
Applications:
WB, Flow, ICC/IF, CyTOF-ready
Detection of Human GSK-3a/ beta  antibody by Western Blot.
(4)

Recombinant Monoclonal Antibody

Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Monoclonal Clone #SY26-05
Applications:
IHC, WB, ICC/IF, IP
(11)
Reactivity:
Human, Mouse, Rat, Porcine, Bovine, +5 More
Details:
Mouse IgG2B Monoclonal Clone #1H8
Applications:
IHC, WB, ICC/IF
Western Blot: GSK-3 alpha/beta Antibody (1H8) [NB110-85523]
(2)
Reactivity:
Human, Mouse
Details:
Mouse IgG2B Monoclonal Clone #833916
Applications:
WB, ICC/IF
Detection of Human GSK 3a and GSK-3 beta  antibody by Western Blot.
(3)
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Monoclonal Clone #23GB4380
Applications:
WB, Flow, ICC/IF, Mycoplasma
GSK-3 alpha/beta [p Tyr279] Antibody (23GB4380)
(4)
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Monoclonal Clone #23GB1100
Applications:
WB, Flow, ICC/IF, Mycoplasma
GSK-3 alpha/beta Antibody (23GB1100)
(4)

Recombinant Monoclonal Antibody

Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Monoclonal Clone #SR1908
Applications:
IHC, WB, ICC/IF, IP

Recombinant Monoclonal Antibody

Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Monoclonal Clone #SR1908
Applications:
IHC, WB, ICC/IF, IP
Reactivity:
Human, Mouse, Rat
Details:
Mouse IgG1 Monoclonal Clone #M132
Applications:
WB
GSK-3 alpha/beta [p Tyr216] Antibody (M132)

Recombinant Monoclonal Antibody

Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Monoclonal Clone #S08-8G7
Applications:
WB
Western Blot: GSK-3 alpha/beta Antibody (S08-8G7) [NBP3-19938]
Reactivity:
Mouse, Rat
Details:
Rabbit IgG Polyclonal
Applications:
WB
Western Blot: GSK-3 alpha/beta [p Ser9] Antibody [NB300-741]

Recombinant Monoclonal Antibody

Reactivity:
Human, Mouse
Details:
Rabbit IgG Monoclonal Clone #L5
Applications:
WB, IP
Western Blot: GSK-3 alpha/beta Antibody (L5) [NBP2-29873]
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