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Granulysin Products
Granulysin, formerly known as NKG5 or Lymphokine LAG-2, is a membrane-lytic protein that is expressed in granules of natural killer and activated cytotoxic T cells. It exhibits cytolytic activity against intracellular or extracellular microbes and also tumors, either alone or in synergy with Perforin. IL-15 is necessary and sufficient for Granulysin release from CD8+ T cells. Granulysin promotes chemotaxis and increases production of chemokines by monocytic cells as well as target cell lysis. It binds and disrupts microbial membranes through charge interactions.
6 results for "Granulysin" in Products
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Granulysin Products
Granulysin, formerly known as NKG5 or Lymphokine LAG-2, is a membrane-lytic protein that is expressed in granules of natural killer and activated cytotoxic T cells. It exhibits cytolytic activity against intracellular or extracellular microbes and also tumors, either alone or in synergy with Perforin. IL-15 is necessary and sufficient for Granulysin release from CD8+ T cells. Granulysin promotes chemotaxis and increases production of chemokines by monocytic cells as well as target cell lysis. It binds and disrupts microbial membranes through charge interactions.
6 results for "Granulysin" in Products
| Assay Range : | 15.6 - 1,000 pg/mL |
| Applications : | ELISA |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Flow Cytometry, Western Blot |
| Source : | NS0 |
| Accession # : | P22749 |
| Applications : | Bioactivity |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | CyTOF-ready, Flow Cytometry, Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #786343 |
| Applications : | ELISA |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #786314 |
| Applications : | ELISA |
