3 results for "GPBA Receptor Agonists" in Products
GPBA Receptor Agonists Products
GPBA receptors (GPBAR1, M-BAR, TGR5) are G protein-coupled receptors (GPCRs) that are activated by bile acids. They are primarily expressed in the gallbladder, ileum and colon, and are important in the regulation of glucose and lipid metabolism, and energy expenditure.
GPBA receptors are members of the class A (rhodopsin-like) subgroup of GPCRs and are present at varying levels in the liver, gallbladder, ileum, colon, heart, spleen, kidney, placenta, leukocytes, skeletal muscle, brown adipose ...
GPBA receptor (TGR5) agonist
| Chemical Name: | 4-[[3,5-Bis(trifluoromethyl)phenyl]methyl]-6-(2-fluorophenyl)-4,5-dihydro-pyrido[3,2-f]-1,4-oxazepin-3(2H)-one |
| Purity: | ≥98% (HPLC) |
Potent and selective GPBA receptor (TGR5) agonist
| Chemical Name: | (4-Cyclopropyl-3,4-dihydro-1(2H)-quinoxalinyl)[4-(2,5-dimethylphenoxy)-3-pyridinyl]methanone |
| Purity: | ≥98% (HPLC) |
Antitumor and anti-HIV agent; activates NF-κB. Also TGR5 agonist
| Chemical Name: | (+)-(3β)-3-Hydroxylup-20(29)-en-28-oic acid |
