Glutathione Reductase: Proteins and Enzymes

Glutathione Reductase (GR) is a homodimeric flavoprotein disulfide oxidoreductase that plays a critical role in the prevention of oxidative damage within the cell. Glutathione Reductase helps to maintain appropriate levels of intracellular reduced glutathione (GSH) which is essential for maintaining the normal structure of red blood cells and for keeping hemoglobin in the ferrous state. Glutathione Reductase together with its co-factor, NADPH, catalyzes the reduction of oxidized glutathione ...