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3 results for "GDF-15 Proteins and Enzymes" in Products
GDF-15 Proteins and Enzymes
GDF-15 (Growth Differentiation Factor 15) is a dimeric TGF-beta superfamily cytokine that is highly expressed in placenta and brain. It promotes neuronal survival and regulates neuropeptide Y and pro-opiomelanocortin levels to suppress appetite. It is cardioprotective via inhibition of platelet activation, limiting atherosclerosis, promoting recovery following myocardial infarction, and regulating angiogenesis. GDF-15 also inhibits cartilage formation and the production of TNF-alpha production from LPS-stimulated macrophages.
Reactivity:
Human
Source:
E. coli
Accession #:
Q99988
Applications:
Bioactivity
Reactivity:
Mouse
Source:
E. coli
Accession #:
Q9Z0J7
Applications:
Bioactivity
Reactivity:
Mouse
Source:
CHO
Accession #:
Q9Z0J7.2
Applications:
Bioactivity
