Recombinant Mouse GDF-15 (CHO-expressed) Protein, CF
Catalog # 10596-GD | R&D Systems, Inc. a Bio-Techne Brand
Key Product Details
Accession #
Source
Structure / Form
Conjugate
Applications
Product Specifications
Source
Ser189-Ala303
Purity
Endotoxin Level
N-terminal Sequence Analysis
Predicted Molecular Mass
SDS-PAGE
Activity
The ED50 for this effect is 0.4-4 ng/mL.
Scientific Data Images for Recombinant Mouse GDF-15 (CHO-expressed) Protein, CF
Recombinant Mouse GDF-15 (CHO-expressed) Protein Bioactivity.
Recombinant Mouse GDF-15 (Catalog # 10596-GD) activates SRE-SEAP reporter in HEK293 human embryonic kidney cells transfected with human c-Ret and human GFRAL. The ED50 for this effect is 0.4-4 ng/mL.Recombinant Mouse GDF-15 (CHO-expressed) Protein SDS-PAGE.
1 μg/lane of Recombinant Mouse GDF-15 (CHO-expressed) Protein (Catalog # 10596-GD) was resolved with SDS-PAGE under reducing (R) and non-reducing (NR) conditions and visualized by silver staining, showing bands at 11-13 kDa and 22-26 kDa, respectively.Formulation, Preparation and Storage
10596-GD
Formulation | Lyophilized from a 0.2 μm filtered solution in HCl. |
Reconstitution | Reconstitute at 500 μg/mL in 4 mM HCl. |
Shipping | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
Stability & Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
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Background: GDF-15
References
- Bootcov, M.R. et al. (1997) Proc. Natl. Acad. Sci. USA 94:11514.
- Böttner, M. et al. (1999) Gene 237:105.
- Fairlie, W.D. et al. (1998) J. Leukoc. Biol 65:2.
- Fairlie, W.D. et al. (2001) J B.C 20:16911.
- Bauskin, A.R. et al. (2000) EMBO J. 19:2212.
- Strelau, J. et al. (2000) J. Neurosci. 20:8597.
- Schober, A. et al. (2001) J. Comp. Neurol. 439:32.
- Mullican, S. et al. (2017) Nat. Med 23:1150.
- Yang, L. et al. (2017) Nat. Med 23:1158.
- Emmerson, P. et al. (2017) Nat. Med 23:1215.
Long Name
Alternate Names
Gene Symbol
UniProt
Product Documents for Recombinant Mouse GDF-15 (CHO-expressed) Protein, CF
Product Specific Notices for Recombinant Mouse GDF-15 (CHO-expressed) Protein, CF
For research use only
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