Gastrin-releasing Peptide R/GRPR: Small Molecules and Peptides
Gastrin-releasing peptide (GRP) is a neuropeptide that acts through G protein-coupled receptors (GPCRs) involved in signal transmission in both central and peripheral nervous systems. Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation. It is a potent mitogen for neoplastic tissues. GRPR is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate.
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1 result for "Gastrin-releasing Peptide R/GRPR Small Molecules and Peptides" in Products
Gastrin-releasing Peptide R/GRPR: Small Molecules and Peptides
Gastrin-releasing peptide (GRP) is a neuropeptide that acts through G protein-coupled receptors (GPCRs) involved in signal transmission in both central and peripheral nervous systems. Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation. It is a potent mitogen for neoplastic tissues. GRPR is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate.
GRP (BB2) and NMB (BB1) receptor antagonist
| Chemical Name: | (S)-N-[[1-(5-Methoxy-2-pyridinyl)cyclohexyl]methyl]-α-methyl-α-[[[-(4-nitrophenyl)amino]carbonyl]amino-1H-indole-3-propanamide |
| Purity: | ≥98% (HPLC) |