Fyn: Small Molecules and Peptides
Fyn is a ubiquitously expressed member of the Src family of intracellular tyrosine kinases. Fyn functions in T cell receptor signaling, adhesion-mediated signaling, and regulation of brain function. Mice lacking fyn display various deficits, including impaired spatial memory, hypomyelination, and uncoordinated hippocampal structure, suggesting that Fyn is involved in multiple neural signaling pathways.
8 results for "Fyn Small Molecules and Peptides" in Products
8 results for "Fyn Small Molecules and Peptides" in Products
Fyn: Small Molecules and Peptides
Fyn is a ubiquitously expressed member of the Src family of intracellular tyrosine kinases. Fyn functions in T cell receptor signaling, adhesion-mediated signaling, and regulation of brain function. Mice lacking fyn display various deficits, including impaired spatial memory, hypomyelination, and uncoordinated hippocampal structure, suggesting that Fyn is involved in multiple neural signaling pathways.
Potent, selective Src family kinase inhibitor
| Chemical Name: | 3-(4-chlorophenyl) 1-(1,1-dimethylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| Purity: | ≥98% (HPLC) |
Highly potent pan-Src/Bcr-Abl inhibitor
| Alternate Names: | BMS-354825 |
| Chemical Name: | N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide |
| Purity: | ≥98% (HPLC) |
Potent and selective Src tyrosine kinase family inhibitor; anticancer; antiviral; orally bioavailable
| Alternate Names: | AZD 0530 |
| Chemical Name: | N-(5-Chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methyl-1-piperazinyl)ethoxy]-5-[(tetrahydro-2H-pyran-4-yl)oxy]-4-quinazolinamine |
| Purity: | ≥98% (HPLC) |
Dual Src-Abl inhibitor; antiproliferative
| Alternate Names: | SKI-606 |
| Chemical Name: | 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile |
| Purity: | ≥98% |
Protein kinase inhibitor
| Alternate Names: | SF 2370 |
| Chemical Name: | (9S,10R,12R)-2,3,9,10,11,12-Hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid methyl ester |
| Purity: | ≥98% (HPLC) |
Src family kinase inhibitor; also inhibits c-Abl
| Alternate Names: | 1-NA-PP 1 |
| Chemical Name: | 1-(1,1-Dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| Purity: | ≥98% (HPLC) |
Potent ATP-competitive Src family kinase inhibitor; also AMPK inhibitor; cell permeable
| Chemical Name: | 2,3-Dihydro-N,N-dimethyl-2-oxo-3-[(4,5,6,7-tetrahydro-1H-indol-2-yl)methylene]-1H-indole-5-sulfonamide |
| Purity: | ≥95% (HPLC) |
Potent, selective Src family kinase inhibitor
| Chemical Name: | 1-(1,1-Dimethylethyl)-1-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| Purity: | ≥98% (HPLC) |
