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25 results for "Fucosyltransferase 5/FUT5" in Products

Fucosyltransferase 5/FUT5 Products

FUT5 (alpha-1, 3-fucosyltransferase 5; also Fuc-TV) is a 43 kDa member of the glycosyltransferase 10 family. It is responsible for the terminal step in the synthesis of Lex, sialy-Lex, and Lea antigens. This is accomplished by the transfer of fucose to preexisting LacNAc or sialyl-LacNAc structures. Human FUT5 is 374 amino acids (aa) in length. It is a type II transmembrane Golgi glycoprotein with a C-terminal lumenal domain (aa 35-374). The catalytic domain spans aa 77-374, while the acceptor-binding motif includes aa 120-126. FUT5 is the product of a single exon gene. Thus, there are no splice variants. FUT5 only occurs in primates; there is no rodent ortholog.

FUT5 has been formulated so that it can be used in the cell surface glycoengineering of living cells, and does not affect cell viability or native phenotype apart from the intended impact on cell glycobiology.

Catalog #: FAB4068AFP555
Catalog #: AF4068AFP555
Catalog #: FAB4068AFP405
Catalog #: FAB4068AFP488
Catalog #: AF4068AFP488
Catalog #: FAB4068AFP647
Catalog #: AF4068AFP594
Catalog #: AF4068AFP680
Catalog #: FAB4068AFP594
Catalog #: AF4068AFP647
Catalog #: AF4068AFP405
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