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152 results for "FIH-1/HIF-1AN" in Products

FIH-1/HIF-1AN Products

Factor Inhibiting HIF1 (FIH) protein facilitates repression of HIF-1 transcriptional activity by binding to VHL, which acts as a transcriptional corepressor. VHL inhibits HIF-1 alpha transactivation function by recruiting histone deacetylases. Involvement of VHL in association with FIH provides a unifying mechanism for the modulation of HIF-1 alpha protein stabilization and transcriptional activation in response to changes in cellular oxygen concentration.

Recombinant Monoclonal Antibody

Recombinant Monoclonal Antibody

Catalog #: NBP3-51394
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