EVI-1 Products
Ectopic virus integration site 1 (EVI-1), also known as MECOM, is a 145 kDa is a transcriptional regulator that interacts with GATA2 and histone methyltransferases. EVI-1 contains 7 tandem N-terminal zinc finger regions (aa 21-239), a central region, and a cluster of 3 more zinc fingers (aa 733-812). Longer isoforms have 189 aa or 64 aa N-terminal extensions. EVI-1 target genes are critical to hematopoietic stem cell proliferation and myeloid differentiation. EVI-1 is overexpressed in acute myelogenous leukemia (AML) as well as ovarian cancer. Chromosomal translocations fuse EVI-1 with RUNX1 and RPN1 contribute to chromosomal instability, myeloid leukemia proliferation, and a block in myeloid differentiation.
55 results for "EVI-1" in Products
55 results for "EVI-1" in Products
EVI-1 Products
Ectopic virus integration site 1 (EVI-1), also known as MECOM, is a 145 kDa is a transcriptional regulator that interacts with GATA2 and histone methyltransferases. EVI-1 contains 7 tandem N-terminal zinc finger regions (aa 21-239), a central region, and a cluster of 3 more zinc fingers (aa 733-812). Longer isoforms have 189 aa or 64 aa N-terminal extensions. EVI-1 target genes are critical to hematopoietic stem cell proliferation and myeloid differentiation. EVI-1 is overexpressed in acute myelogenous leukemia (AML) as well as ovarian cancer. Chromosomal translocations fuse EVI-1 with RUNX1 and RPN1 contribute to chromosomal instability, myeloid leukemia proliferation, and a block in myeloid differentiation.
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, ChIP |
![Immunocytochemistry/ Immunofluorescence: EVI-1 Antibody [NBP2-48848]](https://resources.bio-techne.com/images/products/EVI-1-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-48848-img0003.jpg "Immunocytochemistry/ Immunofluorescence: EVI-1 Antibody [NBP2-48848]")
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #702319 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #702321 |
| Applications: | ICC |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #1E7 |
| Applications: | WB, ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #6A9 |
| Applications: | WB, ELISA |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ELISA |
![Western Blot: EVI-1 Antibody [NBP1-52024]](https://resources.bio-techne.com/images/products/EVI-1-Antibody-Western-Blot-NBP1-52024-img0003.jpg "Western Blot: EVI-1 Antibody [NBP1-52024]")
| Applications: | PAGE |
![SDS-PAGE: Recombinant Human EVI-1 His Protein [NBP2-22647]](https://resources.bio-techne.com/images/products/EVI1-Protein-SDS-Page-NBP2-22647-img0001.jpg "SDS-PAGE: Recombinant Human EVI-1 His Protein [NBP2-22647]")
| Applications: | WB |
![Western Blot: EVI-1 Overexpression Lysate [NBP2-11423]](https://resources.bio-techne.com/images/products/EVI1-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-11423-img0001.jpg "Western Blot: EVI-1 Overexpression Lysate [NBP2-11423]")
| Applications: | WB |
![Western Blot: EVI-1 Overexpression Lysate [NBL1-10364]](https://resources.bio-techne.com/images/products/EVI1-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-10364-img0002.jpg "Western Blot: EVI-1 Overexpression Lysate [NBL1-10364]")
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #702319 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #702319 |
| Applications: | WB |
| Applications: | AC |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #702321 |
| Applications: | ICC/IF |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #702321 |
| Applications: | ICC/IF |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #702321 |
| Applications: | ICC/IF |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #702319 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #702321 |
| Applications: | ICC/IF |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #702319 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #702319 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #702321 |
| Applications: | ICC/IF |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #702319 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #702319 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #702319 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #702321 |
| Applications: | ICC/IF |