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6 results for "E-Cadherin" in Products

E-Cadherin Products

E-Cadherin/Cadherin-1 (ECAD) Is a transmembrane cell adhesion protein. It forms homophilic clusters between epithelial cells and is a critical component of adherens junctions. These junctions are critical for the maintenance of the epithelial barrier and epithelial tissue homeostasis. Decreased E-Cadherin is associated with physiological and pathological epithelial-to-mesenchymal transition (EMT) and cell migration, and E-Cadherin loss contributes to cancer metastasis. The shed ECD is released as a soluble factor that enhances cancer cell motility and EGFR-dependent survival and proliferation.

Reactivity:
Human, Mouse
Details:
Mouse IgG1 kappa Monoclonal Clone #CDH1/1525
Applications:
IHC, WB, Flow, ICC/IF, Endotoxin, + 1 More
Novus Antibodies
Reactivity:
Human, Mouse
Details:
Mouse IgG1 kappa Monoclonal Clone #SPM381
Applications:
IHC, WB, Flow, ICC/IF, CyTOF-ready
Novus Antibodies
Reactivity:
Human, Mouse
Details:
Mouse IgG1 kappa Monoclonal Clone #4A2
Applications:
IHC, WB, Flow, ICC/IF, CyTOF-ready
Novus Antibodies
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