DPPII/QPP/DPP7: Small Molecules and Peptides
As a serine exopeptidase that releases Xaa-Pro dipeptides from the N-terminus of proteins and peptides, DPPII/QPPDPP7 shares some substrate and cleavage specificity with the members of the DPPIV family. These enzymes have high potential for drug discovery. However, structurally DPPII is not a member of the DPPIV family, but belongs to a family that contains lysosomal Pro-X carboxypeptidase/prolylcarboxypeptidase/PRCP and thymus-specific serine peptidase/PRSS16.
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DPPII/QPP/DPP7: Small Molecules and Peptides
As a serine exopeptidase that releases Xaa-Pro dipeptides from the N-terminus of proteins and peptides, DPPII/QPPDPP7 shares some substrate and cleavage specificity with the members of the DPPIV family. These enzymes have high potential for drug discovery. However, structurally DPPII is not a member of the DPPIV family, but belongs to a family that contains lysosomal Pro-X carboxypeptidase/prolylcarboxypeptidase/PRCP and thymus-specific serine peptidase/PRSS16.
Potent DPP IV inhibitor; activates NLRP1b inflammasome
| Alternate Names: | Val-boroPro,BXCL 701 |
| Chemical Name: | B-[(2R)-1-[(2S)-2-Amino-3-methyl-1-oxobutyl]-2-pyrrolidinyl]boronic acid methanesulfonate |
| Purity: | ≥98% (HPLC) |