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3 results for "DNMT1 Activity Assays" in Products

DNMT1 Activity Assays

DNMT1 (DNA methyltransferase 1; also MCMT and CXXC-type Zn finger protein 9) is a 190 kDa member of the C5-methyltransferase family of enzymes. DNMT1 is ubiquitous in expression, and appears during the S-phase of the cell cycle. DNMT1 catalyzes the attachment of a methyl group to the C5 position of CpG cytosines using AdoMet/adenosylmethionine as a co factor. This acts to silence select genes during X chromosome inactivation and tumorigenesis. Human DNMT1 is 1616 amino acids (aa) in length. ...

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Reactivity:
Mouse
Applications:
Func
(2)
Reactivity:
Human
Details:
Mouse IgG2b Kappa Monoclonal Clone #DNMT1/2061
Applications:
IHC
Immunohistochemistry-Paraffin: DNMT1 Antibody (DNMT1/2061) - Azide and BSA Free [NBP3-08482]
(2)
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