Dkk-2: Antibodies
Dickkopf related protein 2 (Dkk-2) is a member of the Dickkopf family of secreted Wnt modulators. Dkk proteins modify Wnt engagement of a receptor complex composed of a Frizzled protein and either LRP-5 or LRP-6. Kremen-1 and Kremen-2 are also high affinity receptors for Dkk-1 and Dkk-2. Depending on the cellular context, Dkk-2 can either activate or inhibit canonical Wnt signaling. Dkk proteins are expressed in mesenchymal tissues and control epithelial transformation. Dkk-2 expression is induced by Wnts in bone and is thought to enhance bone density by promoting terminal differentiation of osteoblasts and mineral deposition.
10 results for "Dkk-2 Primary Antibodies" in Products
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Dkk-2: Antibodies
Dickkopf related protein 2 (Dkk-2) is a member of the Dickkopf family of secreted Wnt modulators. Dkk proteins modify Wnt engagement of a receptor complex composed of a Frizzled protein and either LRP-5 or LRP-6. Kremen-1 and Kremen-2 are also high affinity receptors for Dkk-1 and Dkk-2. Depending on the cellular context, Dkk-2 can either activate or inhibit canonical Wnt signaling. Dkk proteins are expressed in mesenchymal tissues and control epithelial transformation. Dkk-2 expression is induced by Wnts in bone and is thought to enhance bone density by promoting terminal differentiation of osteoblasts and mineral deposition.
10 results for "Dkk-2 Primary Antibodies" in Products
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Immunohistochemistry, Western Blot |
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #994930 |
Applications : | Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry |
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #994930 |
Applications : | Flow Cytometry |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Western Blot |
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #994930 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #994930 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #994930 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #994930 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #994930 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #994930 |
Applications : | Flow Cytometry |