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3 results for "Dkk-1 Proteome Profiler Antibody Arrays" in Products
Dkk-1 Proteome Profiler Antibody Arrays
Dkk-1 (Dickkopf related protein 1) is a secreted antagonist of Wnt/beta-Catenin signaling. It interacts with LRP-6, and internalized complexes of Dkk-1/LRP-6/Kremen 2 can downregulate Wnt signaling. The balance between Wnt signaling and Dkk-1 inhibition is critical for bone formation and homeostasis. In addition, Dkk-1 can act as either a tumor suppressor or promoter of metastasis.
Reactivity:
Rat
Assay Range:
31.2-2000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma)
Applications:
ELISA
Contains 4 membranes - each spotted in duplicate with 40 different cytokine antibodies
Reactivity:
Mouse
Reactivity:
Cynomolgus Monkey
