4 results for "CXCR4 Small Molecules and Peptides" in Products
CXCR4: Small Molecules and Peptides
CXCR4, also known as fusin or LESTR, is a G protein-coupled receptor (GPCR) member of the CXC subfamily of chemokine receptors. Human CXCR4 is 352 amino acids (aa) in length with a predicted molecular weight of 40 kDa. The mouse and rat proteins share 91% aa sequence identity with the human protein. CXCR4 is the chemokine receptor for CXCL12. CXCR4 is a critical regulator of progenitor and stem cell mobilization and recruitment during development and during hematopoiesis. As such, antagonists ...
Highly selective CXCR4 antagonist
| Alternate Names: | JM 3100,Plerixafor |
| Chemical Name: | 1,1'-[1,4-Phenylenebis-(methylene)]-bis-(1,4,8,11-tetraazacyclotetradecane) octahydrochloride |
CXCR4 allosteric agonist
| Purity: | ≥95% (HPLC) |
Potent CXCR4 antagonist
| Chemical Name: | N,N'-Dicyclohexylcarbamimidothioic acid (5,6-dihydro-6,6-dimethylimidazo[2,1-b]thiazol-3-yl)methyl ester dihydrochloride |
| Purity: | ≥98% (HPLC) |
Potent and selective CXCR4 antagonist
| Chemical Name: | N-[[4-(1,4,8,11-Tetraazacyclotetradec-1-ylmethyl)phenyl]methyl]-2-pyridinemethanamine hexahydrobromide |
| Purity: | ≥97% (HPLC) |
