ChemR23: Small Molecules and Peptides
ChemR23, also known as Dez in mouse, is a seven-pass transmembrane, G-protein-associated receptor related to the chemoattractant C3a and C5a complement receptors. Although it shows less than 30% amino acid identity to the chemokine receptor family, it shows significant structural similarity. ChemR23 expression is limited to macrophages and dendritic cells. A ligand for ChemR23 has been identified as Chemerin, also known as Tig-2. Receptor-ligand binding elicits chemotaxis of macrophages and immature, but not mature, dendritic cells.
2 results for "ChemR23 Small Molecules and Peptides" in Products
2 results for "ChemR23 Small Molecules and Peptides" in Products
ChemR23: Small Molecules and Peptides
ChemR23, also known as Dez in mouse, is a seven-pass transmembrane, G-protein-associated receptor related to the chemoattractant C3a and C5a complement receptors. Although it shows less than 30% amino acid identity to the chemokine receptor family, it shows significant structural similarity. ChemR23 expression is limited to macrophages and dendritic cells. A ligand for ChemR23 has been identified as Chemerin, also known as Tig-2. Receptor-ligand binding elicits chemotaxis of macrophages and immature, but not mature, dendritic cells.
Potent CMKLR1 agonist; c-terminal peptide of full length mouse chemerin
| Purity: | ≥95% (HPLC) |
Potent CMKLR1 agonist; c-terminal peptide of full length human chemerin
| Purity: | ≥95% (HPLC) |
