CD47: Antibodies
CD47, also known as Integrin-Associated Protein (IAP) and OA3, is a ubiquitous transmembrane protein that binds to SIRP family members on macrophages, neutrophils, and T cells. These interactions prevent macrophage-mediated clearance of healthy CD47-expressing cells and promote immune cell transmigration across the vascular endothelium. CD47 associates in cis with Fas on T cells and enhances Fas-mediated apoptosis; its ligation promotes T cell anergy and dampens Th1 immune responses. CD47 also associates in cis with several Integrins which can positively or negatively modulate Integrin-mediated function. CD47 binding by Thrombospondin-1 inhibits the angiogenic and vasorelaxant effects of nitric oxide. On dendritic cells and myeloma cells, CD47 ligation by TSP-1 induces giant cell formation and osteoclast differentiation.
29 results for "CD47 Primary Antibodies" in Products
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CD47: Antibodies
CD47, also known as Integrin-Associated Protein (IAP) and OA3, is a ubiquitous transmembrane protein that binds to SIRP family members on macrophages, neutrophils, and T cells. These interactions prevent macrophage-mediated clearance of healthy CD47-expressing cells and promote immune cell transmigration across the vascular endothelium. CD47 associates in cis with Fas on T cells and enhances Fas-mediated apoptosis; its ligation promotes T cell anergy and dampens Th1 immune responses. CD47 also associates in cis with several Integrins which can positively or negatively modulate Integrin-mediated function. CD47 binding by Thrombospondin-1 inhibits the angiogenic and vasorelaxant effects of nitric oxide. On dendritic cells and myeloma cells, CD47 ligation by TSP-1 induces giant cell formation and osteoclast differentiation.
29 results for "CD47 Primary Antibodies" in Products
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Immunohistochemistry, Western Blot |
Clonality : | Polyclonal |
Host : | Sheep IgG |
Applications : | Block/Neutralize, CyTOF-ready, Flow Cytometry, Immunohistochemistry, Knockout Validated, Western Blot |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #472603 |
Applications : | Block/Neutralize, CyTOF-ready, Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #472603 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #472603 |
Applications : | Flow Cytometry |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Flow Cytometry, Immunohistochemistry, Western Blot |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #472603 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Rat IgG1 Clone #974222 |
Applications : | Block/Neutralize, CyTOF-ready, Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #472603 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Rat IgG1 Clone #974214 |
Applications : | CyTOF-ready, Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #472603 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #472603 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #472603 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #472603 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #472603 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Rat IgG1 Clone #974214 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Rat IgG1 Clone #974214 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Rat IgG1 Clone #974214 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Rat IgG1 Clone #974214 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Rat IgG1 Clone #974214 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Rat IgG1 Clone #974214 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Rat IgG1 Clone #974214 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Rat IgG1 Clone #974222 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Rat IgG1 Clone #974222 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Rat IgG1 Clone #974222 |
Applications : | Flow Cytometry |