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CD109 Products

CD109 is a GPI-anchored member of the alpha-2-macroglobulin (A2M) and complement family of proteins. CD109 is expressed on activated T cells and platelets, hematopoietic stem cells, megakaryocyte precursors, vascular endothelial cells, basal and myoepithelial cells of secretory glands, and squamous cell carcinoma. Human CD109 is produced as a 170 kDa - 180 kDa glycoprotein that is autocatalytically processed to 150 kDa and 120 kDa forms. CD109 on keratinocytes binds TGF-beta and associates with TGF-beta RI and TGF-beta RII, resulting in inhibition of TGF-beta signaling. Polymorphisms of CD109 include the platelet-specific Gov antigen and the blood group ABH antigens. Alloantibodies directed against these antigens result in unsuccessful platelet transfusions, neonatal alloimmune thrombocytopenia, and posttransfusion purpura.

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171 results for "CD109" in Products

171 results for "CD109" in Products

CD109 Products

CD109 is a GPI-anchored member of the alpha-2-macroglobulin (A2M) and complement family of proteins. CD109 is expressed on activated T cells and platelets, hematopoietic stem cells, megakaryocyte precursors, vascular endothelial cells, basal and myoepithelial cells of secretory glands, and squamous cell carcinoma. Human CD109 is produced as a 170 kDa - 180 kDa glycoprotein that is autocatalytically processed to 150 kDa and 120 kDa forms. CD109 on keratinocytes binds TGF-beta and associates with TGF-beta RI and TGF-beta RII, resulting in inhibition of TGF-beta signaling. Polymorphisms of CD109 include the platelet-specific Gov antigen and the blood group ABH antigens. Alloantibodies directed against these antigens result in unsuccessful platelet transfusions, neonatal alloimmune thrombocytopenia, and posttransfusion purpura.

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Reactivity: Human
Details: Mouse IgG2a Monoclonal Clone #496920
Applications: Flow, IHC, CyTOF-ready
Detection of CD109 antibody in A431 Human Cell Line antibody by Flow Cytometry.
(2)
Source: NS0
Accession #: Q6YHK3
Applications: Bind
R&D Systems Recombinant Proteins and Enzymes
Reactivity: Human, Mouse
Details: Mouse IgG2a Monoclonal Clone #496920
Applications: Flow
Detection of CD109 antibody in A431 Human Cell Line antibody by Flow Cytometry.
(3)
Reactivity: Human
Details: Mouse IgG2a Monoclonal Clone #496920
Applications: Flow
Reactivity: Human
Details: Mouse IgG2a Monoclonal Clone #496920
Applications: Flow
Reactivity: Human
Details: Mouse IgG2a Monoclonal Clone #496920
Applications: Flow
Reactivity: Human
Details: Mouse IgG2a Monoclonal Clone #496920
Applications: Flow
Detection of CD109 antibody in Human PBMCs antibody by Flow Cytometry.
Reactivity: Human
Details: Rabbit IgG Polyclonal
Applications: IHC
Immunohistochemistry-Paraffin: CD109 Antibody [NBP2-62598]
(5)
Reactivity: Human
Details: Mouse IgG2a Monoclonal Clone #496920
Applications: Flow
Reactivity: Human
Details: Mouse IgG2a Monoclonal Clone #496920
Applications: Flow
Reactivity: Human
Details: Mouse IgG2a Monoclonal Clone #496920
Applications: Flow
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