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9 results for "CCL4/MIP-1 beta Proteins and Enzymes" in Products
CCL4/MIP-1 beta Proteins and Enzymes
CCL4/MIP-1 beta is a beta chemokine that is secreted at sites of inflammation by activated leukocytes, lymphocytes, vascular endothelial cells, and pulmonary smooth muscle cells. It attracts a variety of immune cells to sites of microbial infection as well as to other pathologic inflammation such as allergic asthma and ischemic myocardium. CCL4 is secreted from activated monocytes as a heterodimer with CCL3/MIP-1 alpha. It signals through CCR5, and an N-terminally trimmed form additionally interacts with CCR1 and CCR2. In humans, the ability of CCL4 to bind CCR5 inhibits the cellular entry of M-tropic HIV-1 which utilizes CCR5 as a coreceptor.
Reactivity:
Human
Source:
E. coli
Accession #:
P13236.1
Applications:
Bioactivity
Reactivity:
Mouse
Source:
E. coli
Accession #:
Q5QNV9
Applications:
Bioactivity
Reactivity:
Canine
Source:
E. coli
Accession #:
NP_001005250
Applications:
Bioactivity
Reactivity:
Cotton Rat
Source:
E. coli
Accession #:
AAL16933
Applications:
Bioactivity
Reactivity:
Rat
Source:
E. coli
Accession #:
P50230
Applications:
Bioactivity
Reactivity:
Human
Source:
E. coli
Accession #:
P13236
Applications:
Binding Activity
Reactivity:
Human
Source:
E. coli
Accession #:
P13236
Applications:
Bioactivity, PAGE
Catalog #:
NBP2-35080
Reactivity:
Mouse
Source:
E. coli
Accession #:
P14097
Applications:
Bioactivity, PAGE
Catalog #:
NBP2-35080
Reactivity:
Mouse
Source:
E. coli
Accession #:
P14097
Applications:
Bioactivity, PAGE