3 results for "Caspase Activators" in Products
Caspase Activators Products
Caspases (cysteinyl aspartate proteases) are involved in the signal transduction pathways of apoptosis, necrosis and inflammation. These enzymes can be divided into two major classes - initiators and effectors. The initiator isoforms (caspases-1,-4,-5,-8,-9,-10,-11,-12) are activated by, and interact with, upstream adaptor molecules through protein-protein interaction domains known as CARD and DED.
Effector caspases (-3,-6,-7) are responsible for cleaving downstream substrates and are ...
Promotes apoptosome formation and activates caspase-9/caspase-3 pathway. Selectively induces tumor cell apoptosis
| Chemical Name: | 1-[(3,4-Dichlorophenyl)methyl]-1H-indole-2,3-dione |
| Purity: | ≥98% (HPLC) |
Potent pro-apoptotic anticancer agent; activates caspase-3
| Alternate Names: | CDDP |
| Chemical Name: | cis-Diaminodichloroplatinum |
Activator of procaspase-3; pro-apoptotic
| Chemical Name: | 4-(Phenylmethyl)-1-piperazineacetic acid [[2-hydroxy-3-(2-propenyl)phenyl]methylene]hydrazide |
| Purity: | ≥98% (HPLC) |
