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63 results for "Caspase-8" in Products
Caspase-8 Products
Caspase-8, also known as MCH5, FLICA and MACH alpha 1, is a 28 kDa member of the peptidase C14A family of enzymes. It is widely expressed and is considered an initiating caspase for the apoptotic cascade. Caspase-8 acts on a wide variety of substrates including Pro-Caspases-3, -4, -6, -7, -9 and -10, c-FLIPL and Pro-Caspase‑8 itself. Caspase-8 is recruited to the death-inducing signaling complex (DISC) that forms around the death domains of the oligomerized receptors. Multiple rounds of cleavage generate Caspase-8 p10 and p18 which heterodimerize and then associate into the active tetrameric enzyme containing two p10 and two p18 subunits.
Reactivity:
Multi-Species
Reactivity:
Human, Mouse
Details:
Rabbit IgG Polyclonal
Applications:
WB, Simple Western
(3)
Conjugate
Catalog #
Reactivity:
Human, Mouse
Details:
Goat IgG Polyclonal
Applications:
KO, WB, Simple Western
(4)
Conjugate
Catalog #
Reactivity:
Human
Details:
Mouse IgG2A Monoclonal Clone #84131
Applications:
WB
(2)
Conjugate
Catalog #
Reactivity:
Human
Source:
E. coli
Accession #:
Q14790
Applications:
Enzyme Activity
Conjugate
Catalog #
Reactivity:
Human
Details:
Mouse IgG1 Monoclonal Clone #746109
Applications:
ICC/IF
Conjugate
Catalog #
Reactivity:
Human, Mouse
Details:
Rabbit IgG Polyclonal
Applications:
WB
Conjugate
Catalog #
Reactivity:
Human, Mouse
Details:
Rabbit IgG Polyclonal
Applications:
WB
Conjugate
Catalog #
Reactivity:
Human, Mouse
Details:
Rabbit IgG Polyclonal
Applications:
WB
Conjugate
Catalog #
Reactivity:
Human, Mouse
Details:
Rabbit IgG Polyclonal
Applications:
WB
Conjugate
Catalog #
Reactivity:
Human, Mouse
Details:
Rabbit IgG Polyclonal
Applications:
WB
Conjugate
Catalog #
Reactivity:
Human, Mouse
Details:
Rabbit IgG Polyclonal
Applications:
WB
Conjugate
Catalog #
Reactivity:
Human, Mouse
Details:
Rabbit IgG Polyclonal
Applications:
WB
Conjugate
Catalog #
Reactivity:
Human, Mouse
Details:
Rabbit IgG Polyclonal
Applications:
WB
Conjugate
Catalog #
Reactivity:
Human, Mouse
Details:
Goat IgG Polyclonal
Applications:
KO, WB
Conjugate
Catalog #
Reactivity:
Human, Mouse
Details:
Goat IgG Polyclonal
Applications:
KO, WB
Conjugate
Catalog #
Reactivity:
Human, Mouse
Details:
Goat IgG Polyclonal
Applications:
KO, WB
Conjugate
Catalog #
Reactivity:
Human, Mouse
Details:
Goat IgG Polyclonal
Applications:
KO, WB
Conjugate
Catalog #
Reactivity:
Human, Mouse
Details:
Goat IgG Polyclonal
Applications:
KO, WB
Conjugate
Catalog #
Reactivity:
Human, Mouse
Details:
Goat IgG Polyclonal
Applications:
KO, WB
Conjugate
Catalog #
Reactivity:
Human, Mouse
Details:
Goat IgG Polyclonal
Applications:
KO, WB
Conjugate
Catalog #
Reactivity:
Human, Mouse
Details:
Goat IgG Polyclonal
Applications:
KO, WB
Conjugate
Catalog #
Reactivity:
Human
Details:
Mouse IgG2A Monoclonal Clone #84131
Applications:
WB
Conjugate
Catalog #
Reactivity:
Human
Details:
Mouse IgG2A Monoclonal Clone #84131
Applications:
WB
Conjugate
Catalog #
Reactivity:
Human
Details:
Mouse IgG2A Monoclonal Clone #84131
Applications:
WB
Conjugate
Catalog #