Cannabinoid R1/CB1 Modulators: Small Molecules and Peptides
Cannabinoid Receptors are seven-pass transmembrane proteins that belong to the rhodopsin family of G protein-coupled receptors. There are at least two types of Cannabinoid receptors, CB1R and CB2R, which are activated by a family of endogenous arachidonic acid derivatives, such as the endocannabinoids and D9-THC. CB1R is expressed in the central nervous system and upper GI tract, while CB2R is expressed by selected neuronal cell types and hematopoietic cells.
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Cannabinoid R1/CB1 Modulators: Small Molecules and Peptides
Cannabinoid Receptors are seven-pass transmembrane proteins that belong to the rhodopsin family of G protein-coupled receptors. There are at least two types of Cannabinoid receptors, CB1R and CB2R, which are activated by a family of endogenous arachidonic acid derivatives, such as the endocannabinoids and D9-THC. CB1R is expressed in the central nervous system and upper GI tract, while CB2R is expressed by selected neuronal cell types and hematopoietic cells.
Negative allosteric modulator of CB1 receptors
| Chemical Name: | N-(4-Chlorophenyl)-N'-[3-[6-(1-pyrrolidinyl)-2-pyridinyl]phenyl]urea |
| Purity: | ≥98% (HPLC) |
