Activin RIB/ALK-4 Products
Receptors for the TGF-beta superfamily comprise two groups, the type I and the type II serine/threonine kinases. These kinases are type I transmembrane proteins, and the two subgroups are distinguished by the presence of a glycine/serine-rich juxta-membrane domain found in the type I receptors. Either a type I or type II receptor may initially bind ligand, followed by recruitment of its alternate-type receptor counterpart to generate a heteromeric signaling complex. Type I receptors are referred to as the Activin Receptor-like Kinases (ALKs), while the type II receptors are named for the ligands they bind.
51 results for "Activin RIB/ALK-4" in Products
51 results for "Activin RIB/ALK-4" in Products
Activin RIB/ALK-4 Products
Receptors for the TGF-beta superfamily comprise two groups, the type I and the type II serine/threonine kinases. These kinases are type I transmembrane proteins, and the two subgroups are distinguished by the presence of a glycine/serine-rich juxta-membrane domain found in the type I receptors. Either a type I or type II receptor may initially bind ligand, followed by recruitment of its alternate-type receptor counterpart to generate a heteromeric signaling complex. Type I receptors are referred to as the Activin Receptor-like Kinases (ALKs), while the type II receptors are named for the ligands they bind.
Potent, selective inhibitor of TGF-βRI, ALK4 and ALK7
| Chemical Name: | 4-[4-(1,3-benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide |
| Purity: | ≥99% (HPLC) |
SB 431542 synthesized to cGMP guidelines
| Chemical Name: | 4-[4-(1,3-benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide |
| Purity: | ≥99% |
Selective inhibitor of TGF-βRI, ALK4 and ALK7
| Chemical Name: | 3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide |
| Purity: | ≥98% (HPLC) |
| Source: | NS0 |
| Accession #: | NP_031421 |
| Applications: | Bind |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #3U6I8 |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: Activin RIB/ALK-4 Antibody (3U6I8) [NBP3-16106]](https://resources.bio-techne.com/images/products/Activin-RIB-ALK-4-Antibody-3U6I8-Western-Blot-NBP3-16106-img0005.jpg "Western Blot: Activin RIB/ALK-4 Antibody (3U6I8) [NBP3-16106]")
| Source: | NS0 |
| Accession #: | AAA60556 |
| Applications: | Bind |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #544310 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #544310 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #544310 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #544310 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #544310 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #544310 |
| Applications: | Flow |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #S08-8D6 |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: Activin RIB/ALK-4 Antibody (S08-8D6) [NBP3-19558]](https://resources.bio-techne.com/images/products/Activin-RIB-ALK-4-Antibody-S08-8D6-Western-Blot-NBP3-19558-img0002.jpg "Western Blot: Activin RIB/ALK-4 Antibody (S08-8D6) [NBP3-19558]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: Activin RIB/ALK-4 Antibody [NBP2-39003]](https://resources.bio-techne.com/images/products/Activin-RIB-ALK-4-Antibody-Western-Blot-NBP2-39003-img0002.jpg "Western Blot: Activin RIB/ALK-4 Antibody [NBP2-39003]")
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #544310 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #544310 |
| Applications: | Flow, CyTOF-ready |
| Applications: | AC |
| Applications: | WB |
![Western Blot: Activin RIB/ALK-4 Overexpression Lysate [NBL1-07295]](https://resources.bio-techne.com/images/products/Activin-Receptor-Type-1B-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-07295-img0002.jpg "Western Blot: Activin RIB/ALK-4 Overexpression Lysate [NBL1-07295]")
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #544310 |
| Applications: | Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Block, KO |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #544310 |
| Applications: | Flow, CyTOF-ready |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, Block |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #126822 |
| Applications: | WB, Block |
