ABCG2: Small Molecules and Peptides
ATP-binding cassette transporter ABCG2, also known as MXR, BCRP, or ABCP, is an efflux protein that plays a role in host detoxification of various xenobiotic substrates. It is expressed in the liver, intestine, placenta, and blood brain barrier. Hematopoietic stem cells have also been shown to express ABCG2, with levels falling as the cells become CD34+.
2 results for "ABCG2 Small Molecules and Peptides" in Products
2 results for "ABCG2 Small Molecules and Peptides" in Products
ABCG2: Small Molecules and Peptides
ATP-binding cassette transporter ABCG2, also known as MXR, BCRP, or ABCP, is an efflux protein that plays a role in host detoxification of various xenobiotic substrates. It is expressed in the liver, intestine, placenta, and blood brain barrier. Hematopoietic stem cells have also been shown to express ABCG2, with levels falling as the cells become CD34+.
Potent and selective BCRP inhibitor
| Chemical Name: | (3S,6S,12aS)-1,2,3,4,6,7,12,12a-Octahydro-9-methoxy-6-(2-methylpropyl)-1,4-dioxopyrazino[1',2':1,6]pyrido[3,4-b]indole-3-propanoic acid 1,1-dimethylethyl ester |
| Purity: | ≥98% (HPLC) |
Selective BCRP inhibitor
| Chemical Name: | N-[4-(2-Hydroxyethyl)phenyl]-2-[(4-nitrobenzoyl)amino]benzamide |
| Purity: | ≥98% (HPLC) |
