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What is the Pala Single Cell Sorter and Dispenser?

Pala is a gentle, microfluidic-based single cell dispenser that combines two-laser fluorescence sorting in a fast and easy to use interface. Isolating single cells with fluorescence markers has never been easier with a start-up time of less than 5 minutes and delivery of a 96-well plate of single cells in as little as 2 minutes. The two-laser configuration enables a broad range of fluorescence channels providing flexibility in experimental designs. Pala is extremely gentle on sensitive cell types, such as stem cells, exposing the cells to less than 2 PSI of pressure.

 

Unique Pala Advantages

Fluorescence sorting icon representing the Bio-Techne Pala Cell Sorter and Single Cell Dispenser

Fluorescence Sorting

Two laser configurations: 
488 nm (Blue) + 561 nm (Green): 9 channels 
405 nm (Violet) + 488 nm (Blue): 11 channels

Gentle Light Icon

Gentle on Cells

Pala operates at <2 PSI of pressure to preserve cell health and viability.

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Simple to Use

Pala has a simple software interface that prompts users though critical start up, shutdown, or sample switch procedures. No specialized training is required.

Single Cell Sorting

Pala Single Cell Sorting and Single Cell Dispensing instrument workflow vs. competitor workflow

How Does Pala Work?

Leverage the powerful combination of microfluidics, flow cytometry, and liquid dispensing in Pala: 

  • Liquid Dispensing: Isolate single cells into 96- or 384-well plates according to your fluorescence selection criteria.
  • Microfluidic Cartridge: Enable sterile sorting and easy sample switching with no chance for carryover.
  • Flow Cytometry: Detect fluorescent labels or expressed proteins and gate cells of interest for sorting.

Meet Pala

Bio-Techne Pala Cell Sorter and Single Cell Dispenser

Pala Single Cell Sorter and Dispenser

Configured with two lasers for up to 11 detection channels.

Disposable microfluidic cell cartridge used with the Bio-Techne Pala Cell Sorter and Single Cell Dispenser

Microfluidic Cell Cartridges

Disposable and sterile cell cartridge preventing cross contamination.

 Pala
Laser 1488 nm
Laser 2405 nm or 561 nm
Detection ChannelsUp to 11 channels, Forward & Total Scatter
Dimensions25 x 14 x 9"
Weight35 lbs

Hear From Your Peers

Dr. Oscar Perez-Leal describes how his team leveraged a Bio-Techne Single Cell Sorter and Single Cell Dispenser to improve clonal outgrowth of CRISPR-edited cells.

Dr. Oscar Perez-Leal from Temple University describes how his team leveraged a Bio-Techne Single Cell Dispenser to improve clonal outgrowth of CRISPR-edited cells.

Dr. Lina Chakrabarti from AstraZeneca discusses how the single cell sorting dispensing technology on the Pala™ system boosted cell line development workflows for biopharmaceutical manufacturing.

Dr. Lina Chakrabarti from AstraZeneca discusses how the single cell dispenser technology on the Pala™ system boosted cell line development workflows for biopharmaceutical manufacturing.

Dr. Paula Lam Headshot - light gray

Dr. Paula Lam from BioCell Innovations expounds on the successful use of Pala to sort 293T suspension clones, leading to the production of high lentiviral titers.