Mexiletine hydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 2596

Na+ channel blocker; antiarrhythmic agent
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Key Product Details

Description

Na+ channel blocker; antiarrhythmic agent

Alternative Names

Ko 1173

View all Voltage-gated Sodium Channel Blockers »

Product Description

Mexiletine hydrochloride is an use-dependent sodium channel blocker (IC50 values are 75.3 and 23.6 μM for tonic and use-dependent block respectively). Class Ib antiarrhythmic, neuroprotective and antimyotonic agent.

Product Specifications

Molecular Weight

215.72

Formula

C11H17NO.HCl

Storage

Desiccate at +4°C

Purity

≥98% (HPLC)

Chemical Name

1-(2,6-Dimethylphenoxy)-2-propanamine hydrochloride

CAS Number

5370-01-4

PubChem ID

21467

InChI Key

NFEIBWMZVIVJLQ-UHFFFAOYSA-N

SMILES

Cl.CC(N)COC1=C(C)C=CC=C1C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 21.57 100
DMSO 21.57 100

Preparing Stock Solutions for Mexiletine hydrochloride

The following data is based on the product molecular weight 215.72

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.64 mL 23.18 mL 46.36 mL
5 mM 0.93 mL 4.64 mL 9.27 mL
10 mM 0.46 mL 2.32 mL 4.64 mL
50 mM 0.09 mL 0.46 mL 0.93 mL

Calculators

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for Mexiletine hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Mexiletine hydrochloride

For research use only

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