DLin-MC3-DMA

Tocris Bioscience, part of Bio-Techne | Catalog # 7946

Component of lipid nanoparticles (LNPs); ionizable cationic lipid
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Key Product Details

Description

Component of lipid nanoparticles (LNPs); ionizable cationic lipid

View all Lipid Nanoparticle Components Supplemental Kits and Reagents »

Product Description

DLin-MC3-DMA is an ionizable cationic lipid (pKa = 6.44), used in combination with other lipids in the formation of lipid nanoparticles (LNPs) for delivering cargos such as oligonucleotides into living cells. DLin-MC3-DMA can protect negatively charged cargos and facilitate their cytosolic transport.

This product is supplied pre-dissolved in anhydrous ethanol, 100mg/mL

For a fully formulated LNP containing DLin-MC3-DMA and a luciferase mRNA reporter, see MC3 LNP Luciferase (Cat. No. 8889).

For more information on how to prepare MC3 lipid nanoparticles for RNA delivery, please see our protocol.

Product Specifications

Molecular Weight

642.09

Formula

C43H79NO2

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

(6Z,9Z,28Z,31Z)-Heptatriaconta-6,9,28,31-tetraen-19-yl 4-(dimethylamino)butanoate

CAS Number

1224606-06-7

InChI Key

NRLNQCOGCKAESA-KWXKLSQISA-N

SMILES

C(OC(CCCN(C)C)=O)(CCCCCCCC/C=C\C/C=C\CCCCC)CCCCCCCC/C=C\C/C=C\CCCCC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble in ethanol (supplied pre-dissolved in anhydrous ethanol, 100mg/mL)

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Background References

References are publications that support the biological activity of the product.

Product Documents for DLin-MC3-DMA

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for DLin-MC3-DMA

For research use only

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