CpG oligodeoxynucleotides
Novus Biologicals, part of Bio-Techne | Catalog # NBP2-31134
Key Product Details
Species
Human
Applications
Functional Assay
Product Summary for CpG oligodeoxynucleotides
Human Sequence CpG ODN (2006) Type B: 5' T*C*G*T*C*G*T*T*T*T*G*T*C*G*T*T*T*T*G*T*C*G*T*T 3'
(* Indicates a phosphorothioate modification)
Negative Control oligo: 5' TGCTGCTTTTGTGCTTTTGTGCTT 3'
Functionality: This product is useful for the activation of TLR9 and the stimulation of TLR9 has been reported with 5-20 ug/ml.
Product Specifications
Specificity
CpG ODN Type B (2006)
Applications
Functional (reported in scientific literature (PMID 25957979))
In vitro assay (reported in scientific literature (PMID 25957979))
Ligand Activation (5-20 ug/ml)
In vitro assay (reported in scientific literature (PMID 25957979))
Ligand Activation (5-20 ug/ml)
Application Notes
A TLR9/NF-kB SEAP reporter construct in a HEK 293 cell line was used as a model system for studying hTLR9 activation.
Formulation, Preparation, and Storage
Formulation
Sterile water
Concentration
Please see the protocols for proper use of this product. If no protocol is available, contact technical services for assistance.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Background: CpG oligodeoxynucleotides
Alternate Names
CpG ODN, CpG ODN (2006), oligodeoxynucleotides (ODN)
Additional CpG oligodeoxynucleotides Products
Product Documents for CpG oligodeoxynucleotides
Product Specific Notices for CpG oligodeoxynucleotides
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Support products are guaranteed for 6 months from date of receipt.
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