Click N-Acetylmuramic acid - azide
Tocris Bioscience, part of Bio-Techne | Catalog # 7506
Bacterial peptidoglycan derivative; suitable for 'click'-conjugation to fluorescent dyes
Key Product Details
Description
Bacterial peptidoglycan derivative; suitable for 'click'-conjugation to fluorescent dyes
Product Description
Click N-Acetylmuramic acid-azide is a derivative of the N-acetylmuramic acid (NAM) component of bacterial peptidoglycans. Incorporated into bacterial peptidoglycans during biosynthesis. Suitable for fluorescent labeling of peptidoglycans when ''click'-conjugated to a fluorescent dye.Licensing Information
Sold under license from the University of DelawareProduct Specifications
Molecular Weight
334.29
Formula
C11H18N4O8
Storage
Store at -20°C
Purity
≥95% (HPLC)
Chemical Name
(2R)-2-(((3R,4R,5S,6R)-3-(2-Azidoacetamido)-2,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl)oxy)propanoic acid
CAS Number
2245794-64-1
InChI Key
BDRSICZLRYBNHJ-HONWWXKESA-N
SMILES
C[C@H](C(O)=O)O[C@H]1[C@@H]([C@H](OC([C@@H]1NC(CN=[N+]=[N-])=O)O)CO)O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 1.67 | 5 |
Preparing Stock Solutions
for Click N-Acetylmuramic acid - azide
The following data is based on the product molecular weight 334.29
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.05 mM | 59.83 mL | 299.14 mL | 598.28 mL |
| 0.25 mM | 11.97 mL | 59.83 mL | 119.66 mL |
| 0.5 mM | 5.98 mL | 29.91 mL | 59.83 mL |
| 2.5 mM | 1.20 mL | 5.98 mL | 11.97 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Taylor Localizing peptidoglycan synthesis in helicobacter pylori using clickable metabolic probes. Curr.Protoc. 2021e PMID: 33844460
- Wodzanowski Multiscale invasion assay for probing macrophage response to gram-negative bacteria. Front.Chem. 2022 PMID: 35242744
- DeMeester Synthesis of functionalized N-acetyl muramic acids to probe bacterial cell wall recycling and biosynthesis. J.Am.Chem.Soc. 2018 PMID: 29986130
- Wodzanowski Tools for probing host-bacteria interactions in the gut microenvironment: from molecular to cellular levels. Bioorg.Med.Chem.Lett. 2020 PMID: 32223923
- Liang Metabolic labelling of the carbohydrate core in bacterial peptidoglycan and its applications. Nat. Commun. 2017 PMID: 28425464
Product Specific Notices for Click N-Acetylmuramic acid - azide
For research use only
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