Pimonidazole

Name: Pimonidazole
Brand: Tocris Bioscience
SKU: 6182
Rating: 5 (1 reviews)

Tocris Bioscience, part of Bio-Techne | Catalog # 6182

(1)

Citations (1)

COA / SDS

Hypoxia detection reagent

Key Product Details

Description:	Hypoxia detection reagent
Chemical Name:	α-[(2-Nitro-1H-imidazol-1-yl)methyl]-1-piperidineethanol
Purity:	≥98% (HPLC)
Molecular Weight:	254.29

View Full Technical Details for Pimonidazole

Technical Data
Citations / Reviews (1)

Biological Activity for Pimonidazole

Pimonidazole is a hypoxia detection reagent. Labels hypoxic tumor cells in vivo. Also labels hypoxic mesenchymal stem cells in mouse bone marrow.

Technical Data for Pimonidazole

M. Wt	254.29
Formula	C₁₁H₁₈N₄O₃
Storage	Store at -20°C
Purity	≥98% (HPLC)
CAS Number	70132-50-2
PubChem ID	50981
InChi Key	WVWOOAYQYLJEFD-UHFFFAOYSA-N
Smiles	OC(CN1CCCCC1)CN2C=CN=C2[N+]([O-])=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Pimonidazole

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	DMSO	25.43	100
	ethanol	25.43	100

Preparing Stock Solutions for Pimonidazole

The following data is based on the product molecular weight 254.29.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.93 mL	19.66 mL	39.33 mL
5 mM	0.79 mL	3.93 mL	7.87 mL
10 mM	0.39 mL	1.97 mL	3.93 mL
50 mM	0.08 mL	0.39 mL	0.79 mL

Molarity Calculator

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Reconstitution Calculator

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References for Pimonidazole

References are publications that support the biological activity of the product.

Bennewith Orally administered pimonidazole to label hypoxic tumor cells. Cancer Res. 2002 PMID: 12460894
Sato Notch2 signaling regulates the proliferation of murine bone marrow-derived mesenchymal stem/stromal cells via c-Myc expression. PLoS One 2016 PMID: 27855169