JC-1 mitochondrial membrane potential dependent fluorescent dye

Name: JC-1 mitochondrial membrane potential dependent fluorescent dye
Brand: Novus Biologicals
SKU: NBP2-62754

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-62754

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Key Product Details

Applications

Block/Neutralize, N/A

Product Summary for JC-1 mitochondrial membrane potential dependent fluorescent dye

Mitochondrial membrane potential dependent fluorescent dye
Purity:>98% (HPLC); NMR (conforms)
CAS No.: 3520-43-2
Molecular Formula C₂₅H₂₇Cl₄IN₄
Molecular Weight:652.2
Source:Synthetic
Appearance:Red powder
PubChem ID: 5492929

Product Specifications

Application Notes

Red powder. May be dissolved in water (50 mg/mL); DMSO (15 mg/mL).

Scientific Data Images for JC-1 mitochondrial membrane potential dependent fluorescent dye

Product Image: JC-1 mitochondrial membrane potential dependent fluorescent dye [NBP2-62754] - Chemical structure of JC-1 (NBP2-62754), a Mitochondrial membrane potential dependent fluorescent dye. Molecular Formula: C25H27Cl4IN4. Molecular Weight: 652.2 g/mol.

Formulation, Preparation, and Storage

Concentration

Please see the protocols for proper use of this product. If no protocol is available, contact technical services for assistance.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: JC-1 mitochondrial membrane potential dependent fluorescent dye

JC-1 is a fluorescent dye that is able to pass across the mitochondrial membrane. It is used to measure mitochondrial membrane potential. At low membrane potentials, it remains a monomer and emits green-fluorescent light (Lambdaex=485 nm, Lambdaem=520 nm). At higher membrane potentials, it forms "J-aggregates", which emit red-fluorescent light (Lambdaex=520-570 nm, Lambdaem=570-610 nm). The ratio of red/green fluorescence is based only on the membrane potential, and not on mitochondrial size, shape or density.

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Product Specific Notices for JC-1 mitochondrial membrane potential dependent fluorescent dye

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Support products are guaranteed for 6 months from date of receipt.

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