Sotalol hydrochloride
Tocris Bioscience, part of Bio-Techne | Catalog # 0952
β antagonist
Key Product Details
Description
β antagonist
Product Description
Sotalol hydrochloride is a relatively potent pure β adrenergic antagonist, unique in possessing additional class III antiarrhythmic activity.Product Specifications
Molecular Weight
308.82
Formula
C12H20N2O3S.HCl
Storage
Store at RT
Purity
≥98% (HPLC)
Chemical Name
N-[4-[1-Hydroxy-2-[(1-methylethyl)amino]ethyl]phenyl]methanesulfonamide hydrochloride
CAS Number
959-24-0
PubChem ID
66245
InChI Key
VIDRYROWYFWGSY-UHFFFAOYSA-N
SMILES
Cl.CC(C)NCC(O)C1=CC=C(NS(C)(=O)=O)C=C1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 15.44 | 50 |
Preparing Stock Solutions
for Sotalol hydrochloride
The following data is based on the product molecular weight 308.82
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.5 mM | 6.48 mL | 32.38 mL | 64.76 mL |
| 2.5 mM | 1.30 mL | 6.48 mL | 12.95 mL |
| 5 mM | 0.65 mL | 3.24 mL | 6.48 mL |
| 25 mM | 0.13 mL | 0.65 mL | 1.30 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Fiset Block of Iks by the diuretic agent indap. modulates cardiac electrophysiological effects of the class III antiarrhythmic drug dl-sotalol. J.Pharmacol.Exp.Ther. 1997 PMID: 9336319
- Uloth Sulfonanilides. I. Monoalkyl- and arylsulfonamidophenethanolamines. J.Med.Chem. 1966 PMID: 6006227
- Claudel and Touboul Sotalol: from 'just another beta blocker' to 'the prototype class III antidysrhythmic compound'. Pacing Clin.Electrophysiol. 1995 PMID: 7770366
Product Specific Notices for Sotalol hydrochloride
For research use only
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