FURA-2AM

Tocris Bioscience, part of Bio-Techne | Catalog # 2220

Fluorescent Ca2+ indicator
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Key Product Details

Description

Fluorescent Ca2+ indicator

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Product Description

FURA-2AM is a fluorescent ratiometric Ca2+ indicator (Kd Ca2+ = 145 nM). FURA-2AM is selective for Ca2+ over other divalent cations Mg2+, Zn2+, Fe2+ and Mn2+. FURA-2AM binds to free intracellular calcium and is used to determine [Ca2+]i concentration.

This product is typically prepared in DMSO. F 127 (Cat. No. 6253) for the solubilization of FURA-2AM is also available.

Optical Data

λabs 371 nm
λem 474 nm
Extinction Coefficient (ε) 30000 M-1cm-1
Cell Permeable Yes
Application Flow Cytometry, Fluorescent Microscopy

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Product Specifications

Molecular Weight

1001.85

Formula

C44H47N3O24

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

2-[6-[bis[2-[(Acetyloxy)methoxy]-2-oxoethyl]amino]-5-[2-[2-[bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]-5-methylphenoxy]ethoxy]-2-benzofuranyl]-5-oxazolecarboxylic acid (acetyloxy)methyl ester

CAS Number

108964-32-5

PubChem ID

90488749

InChI Key

JTDRWQMCMPIBNJ-UHFFFAOYSA-N

SMILES

CC1=CC(OCCOC2=C(N(CC(OCOC(C)=O)=O)CC(OCOC=O)=O)C=C(OC(C4=NC=C(C(OCOC(C)=O)=O)O4)=C3)C3=C2)=C(N(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Background References

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Product Documents for FURA-2AM

Certificate of Analysis

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Product Specific Notices for FURA-2AM

For research use only

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