FFN 102 mesylate
Tocris Bioscience, part of Bio-Techne | Catalog # 5200
Selective fluorescent substrate of DAT and VMAT2
Key Product Details
Description
Selective fluorescent substrate of DAT and VMAT2
Product Description
FFN 102 mesylate is a pH responsive fluorescent false neurotransmitter (FFN). Selective dopamine transporter (DAT) and VMAT2 substrate. Exhibits no significant binding to a panel of 38 CNS receptors, including dopamine and serotonin receptors. Inhibits dopamine uptake. Excitation maxima are 340 nm at pH 5 and 370 nm at pH 7.5. Emission maximum is 435 nm at both pH 5 and 7.5.Licensing Information
Sold with the permission of Columbia University.Spectra Viewer
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Product Specifications
Molecular Weight
335.76
Formula
C11H10NClO3.CH3SO3H
Storage
Desiccate at +4°C
Purity
≥98% (HPLC)
Chemical Name
4-(2-Aminoethyl)-6-chloro-7-hydroxy-2H-1-benzopyran-2-one methanesulfonate
CAS Number
1883548-92-2
PubChem ID
91691121
InChI Key
ZEZDFYRVIVZPAT-UHFFFAOYSA-N
SMILES
ClC1=C(O)C=C(OC(C=C2CCN)=O)C2=C1.CS(=O)(O)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 6.72 | 20 with gentle warming | |
| DMSO | 33.58 | 100 |
Preparing Stock Solutions
for FFN 102 mesylate
The following data is based on the product molecular weight 335.76
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.98 mL | 14.89 mL | 29.78 mL |
| 5 mM | 0.60 mL | 2.98 mL | 5.96 mL |
| 10 mM | 0.30 mL | 1.49 mL | 2.98 mL |
| 50 mM | 0.06 mL | 0.30 mL | 0.60 mL |
Calculators
Molarity Calculator
Dilution Calculator
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Background References
References are publications that support the biological activity of the product.
- Sames Visualizing neurotransmitter secretion at individual synapses. ACS Chem.Neurosci. 2013 PMID: 23862751
- Lee Development of pH-responsive fluorescent false neurotransmitters. J.Am.Chem.Soc. 2010 PMID: 20540519
- Rodriguez Fluorescent DA tracer resolves individual DArgic synapses and their activity in the brain. Proc.Natl.Acad.Sci.U.S.A. 2013 PMID: 23277566
Product Specific Notices for FFN 102 mesylate
For research use only
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