Zanamivir

Tocris Bioscience, part of Bio-Techne | Catalog # 7187

Potent influenza virus neuraminidase inhibitor
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Key Product Details

Description

Potent influenza virus neuraminidase inhibitor

View all Hydrolase Inhibitors »

Product Description

Zanamivir is an influenza viral neuraminidase inhibitor (IC50 values are 0.95 nM and 2.7 nM for influenza A and B, respectively). Inhibits neuraminidase, preventing the cleavage of sialic acid on the cell receptors, and release of the newly formed virions.

Product Specifications

Molecular Weight

332.31

Formula

C12H20N4O7

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

5-(Acetylamino)-4-[(aminoiminomethyl)amino]-2,6-anhydro-3,4,5-trideoxy-5-(Acetylamino)-4-[(aminoiminomethyl)amino]-2,6-anhydro-3,4,5-trideoxy-D-glycero-D-galactonon-2-enonic acid-glycero-D-galactonon-2-enonic acid

CAS Number

139110-80-8

PubChem ID

60855

InChI Key

ARAIBEBZBOPLMB-UFGQHTETSA-N

SMILES

[H][C@]1(OC(=C[C@H](NC(N)=N)[C@H]1NC(C)=O)C(O)=O)[C@H](O)[C@H](O)CO

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 1.66 5

Preparing Stock Solutions for Zanamivir

The following data is based on the product molecular weight 332.31

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.05 mM 60.18 mL 300.92 mL 601.85 mL
0.25 mM 12.04 mL 60.18 mL 120.37 mL
0.5 mM 6.02 mL 30.09 mL 60.18 mL
2.5 mM 1.20 mL 6.02 mL 12.04 mL

Calculators

Molarity Calculator

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Dilution Calculator

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Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background References

References are publications that support the biological activity of the product.

Product Documents for Zanamivir

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Zanamivir

For research use only

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