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Withaferin A

Tocris Bioscience a Bio-Techne Brand

Withaferin A | CAS No. 5119-48-2 | Inhibits NF-κB activation
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Key Product Details

Description: Inhibits NF-κB activation
Chemical Name: (4β,5β,6β,22R)-5,6-Epoxy-4,22,27-trihydroxy-1-oxoergosta-2,24-dien-26-oic acid δ-lactone
Purity: ≥98% (HPLC)
Molecular Weight: 470.6

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Citations for Withaferin A (7)

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Customer Reviews for Withaferin A (2)

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  • 42 perturbagens used the zebrafish DASPEI screen
    Name: Anonymous
    Species: Other
    Assay Type: In Vivo
    Cell Line/Tissue: larvae
    Zebrafish larvae were placed into 48-well plates and used the DASPEI screen by 42 perturbagens drugs, including this compound
    Withaferin A Serum 2816
  • Withaferin inhibits LPS-induced TNFalpha production in macrophages
    Name: Christopher Trummer
    Species: Mouse
    Assay Type: In Vitro
    Cell Line/Tissue: Macrophages
    RAW macrophages were stimulated with Withaferin (1 µM) alone or in the presence of LPS (200 ng/ml) for 8 h to follow TNFalpha mRNA expression using qPCR. Withaferin significantly inhibited LPS-induced TNFalpha production.
    Withaferin A Serum 2816

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Product Documents for Withaferin A

Certificate of Analysis

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