WIN 18446

Tocris Bioscience, part of Bio-Techne | Catalog # 4736

ALDH1A2 inhibitor
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Key Product Details

Description

ALDH1A2 inhibitor

View all Aldehyde Dehydrogenase Inhibitors »

Product Description

WIN 18446 is an inhibitor of aldehyde dehydrogenase 1a2 (ALDH1a2) (IC50 = 0.3 μM). Inhibits the biosynthesis of retinoic acid from retinol in neonatal and adult murine testis.

Product Specifications

Molecular Weight

366.11

Formula

C12H20Cl4N2O2

Storage

Store at +4°C

Chemical Name

N,N'-1,8-Octanediylbis(2,2-dichloroacetamide)

CAS Number

1477-57-2

PubChem ID

15134

InChI Key

FAOMZVDZARKPFJ-UHFFFAOYSA-N

SMILES

ClC(Cl)C(NCCCCCCCCNC(C(Cl)Cl)=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 36.61 100

Preparing Stock Solutions for WIN 18446

The following data is based on the product molecular weight 366.11

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.73 mL 13.66 mL 27.31 mL
5 mM 0.55 mL 2.73 mL 5.46 mL
10 mM 0.27 mL 1.37 mL 2.73 mL
50 mM 0.05 mL 0.27 mL 0.55 mL

Calculators

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for WIN 18446

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for WIN 18446

For research use only

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