WAY 267464 dihydrochloride
Tocris Bioscience, part of Bio-Techne | Catalog # 3933
Potent non-peptide oxytocin receptor agonist
Key Product Details
Description
Potent non-peptide oxytocin receptor agonist
Product Description
WAY 267464 dihydrochloride is a potent, selective non-peptide oxytocin receptor (OTR) agonist (Ki = 58.4 nM at human OTR). Exhibits anxiolytic-like effects. May have therapeutic potential for the treatment of psychosis and schizophrenia.Licensing Information
Sold for research purposes under agreement from Pfizer Inc.Product Specifications
Molecular Weight
654.59
Formula
C32H35N7O4.2HCl
Storage
Store at -20°C
Purity
≥97% (HPLC)
Chemical Name
N-[[4-[(4,10-Dihydro-1-methylpyrazolo[3,4-b][1,5]benzodiazepin-5(1H)-yl)carbonyl]-2-methylphenyl]methyl]-4-[(3,5-dihydroxyphenyl)methyl]-1-piperazinecarboxamide dihydrochloride
CAS Number
1432043-31-6
PubChem ID
71555165
InChI Key
OTFWXMFLPMUDFP-UHFFFAOYSA-N
SMILES
CN(N=C3)C1=C3CN(C(C4=CC=C(CNC(N5CCN(CC6=CC(O)=CC(O)=C6)CC5)=O)C(C)=C4)=O)C(C=CC=C2)=C2N1.Cl.Cl
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 3.27 | 5 | |
| DMSO | 52.37 | 80 |
Preparing Stock Solutions
for WAY 267464 dihydrochloride
The following data is based on the product molecular weight 654.59
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.8 mM | 1.91 mL | 9.55 mL | 19.10 mL |
| 4 mM | 0.38 mL | 1.91 mL | 3.82 mL |
| 8 mM | 0.19 mL | 0.95 mL | 1.91 mL |
| 40 mM | 0.04 mL | 0.19 mL | 0.38 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Ring Receptor and behavioral pharmacology of WAY-267464, a non-peptide oxyt. receptor agonist. Neuropharmacology 2010 PMID: 19615387
Product Specific Notices for WAY 267464 dihydrochloride
For research use only
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