Key Product Details
Description: | Calmodulin antagonist. Inhibits myosin light chain kinase |
Chemical Name: | N-(6-Aminohexyl)-5-chloro-1-naphthalenesulfonamide hydrochloride |
Purity: | ≥98% (HPLC) |
Molecular Weight: | 377.33 |
Complete Your Research
Citations for W-7 hydrochloride (16)
Citations are publications that use Bio-Techne products. Selected citations for W-7 hydrochloride include:
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Lopez et al.
(2022)
Ketamine exerts its sustained antidepressant effects via cell-type-specific regulation of Kcnq2.
Neuron.
110:2283
PMID: 35649415 -
Schiff et al.
(2019)
P38 inhibition reverses TGFβ1 and TNFα-induced contraction in a model of proliferative vitreoretinopathy.
Commun Biol.
2:162
PMID: 31069271 -
Haag et al.
(2018)
The Actin Nucleator Cobl Is Critical for Centriolar Positioning, Postnatal Planar Cell Polarity Refinement, and Function of the Cochlea.
Cell Rep.
24:2418
PMID: 30157434 -
Yanda et al.
(2017)
Histone deacetylase 6 inhibition reduces cysts by decreasing cAMP and Ca(2+) in knock-out mouse models of polycystic kidney disease.
J Biol Chem.
292:17897
PMID: 28887310 -
Gray and Golowasch
(2016)
Voltage Dependence of a Neuromodulator-Activated Ionic Current.
Eneuro.
3
PMID: 27257619 -
Yuan et al.
(2015)
Protein kinase G-regulated production of H2S governs oxygen sensing.
Sci Signal.
8:ra37
PMID: 25900831 -
Hou et al.
(2015)
The Actin Nucleator Cobl Is Controlled by Calcium and Calmodulin.
Apoptosis.
13:e1002233
PMID: 26334624 -
Bonnefond et al.
(2015)
Calcium signals inhibition sensitizes ovarian carcinoma cells to anti-Bcl-xL strategies through Mcl-1 down-regulation.
J Biol Chem.
20:535
PMID: 25627260 -
Araki et al.
(2015)
Rapid dispersion of SynGAP from synaptic spines triggers AMPA receptor insertion and spine enlargement during LTP.
J Neurosci.
85:173
PMID: 25569349 -
Mukunda et al.
(2014)
Dimerisation of the Drosophila odorant coreceptor Orco.
Neuron.
8:261
PMID: 25221476 -
Chang et al.
(2013)
Areca nut-induced buccal mucosa fibroblast contraction and its signaling: a potential role in oral submucous fibrosis--a precancer condition.
Psychopharmacology (Berl).
34:1096
PMID: 23349021 -
Abdou et al.
(2013)
The calcium signaling pathway regulates leydig cell steroidogenesis through a transcriptional cascade involving the nuclear receptor NR4A1 and the steroidogenic acute regulatory protein.
Endocrinology.
154:511
PMID: 23183170 -
Midkiff et al.
(2011)
Small molecule inhibitors of the Candida albicans budded-to-hyphal transition act through multiple signaling pathways.
PLoS One.
6:e25395
PMID: 21966518 -
Dai et al.
(2011)
Phospholipase C, Ca2+, and calmodulin signaling are required for 5-HT2A receptor-mediated transamidation of Rac1 by transglutaminase.
Front Cell Neurosci.
213:403
PMID: 20717650 -
Yanes and Romero
(2009)
Dihydrotestosterone stimulates aldosterone secretion by H295R human adrenocortical cells.
Mol Cell Endocrinol.
303:50
PMID: 19428991 -
Long et al.
(2009)
Nerve Terminal GABAA Receptors Activate Ca2+/Calmodulin-dependent Signaling to Inhibit Voltage-gated Ca2+ Influx and Glutamate Release.
Carcinogenesis.
284:8726
PMID: 19141616
There are no citations that match your criteria.
Customer Reviews for W-7 hydrochloride (1)
Customer Images
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Species: MouseAssay Type: In VitroCell Line/Tissue: PN and PH cellsPN and PH cells were treated with W-7 (catalog no. 0369) and W-13(catalog no. 0361) purchased from Tocris.
There are no reviews that match your criteria.