Vilazodone hydrochloride
Tocris Bioscience, part of Bio-Techne | Catalog # 6202
Potent 5-HT1A partial agonist and SSRI; antidepressant
Key Product Details
Description
Potent 5-HT1A partial agonist and SSRI; antidepressant
Alternative Names
EMD 68843,SB 659746A
Product Description
Vilazodone hydrochloride is a potent 5-HT1A partial agonist and serotonin-selective reuptake inhibitor (SSRI) (IC50 values are 0.2 and 0.5 nM respectively). Antidepressant.Product Specifications
Molecular Weight
477.99
Formula
C26H27N5O2.HCl
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
5-[4-[4-(5-Cyano-1H-indol-3-yl)butyl]-1-piperazinyl]-2-benzofurancarboxamide hydrochloride
CAS Number
163521-08-2
PubChem ID
6918313
InChI Key
RPZBRGFNBNQSOP-UHFFFAOYSA-N
SMILES
NC(C1=CC2=C(C=CC(N3CCN(CC3)CCCCC4=CNC5=C4C=C(C#N)C=C5)=C2)O1)=O.Cl
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 9.56 | 20 |
Preparing Stock Solutions
for Vilazodone hydrochloride
The following data is based on the product molecular weight 477.99
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.2 mM | 10.46 mL | 52.30 mL | 104.60 mL |
| 1 mM | 2.09 mL | 10.46 mL | 20.92 mL |
| 2 mM | 1.05 mL | 5.23 mL | 10.46 mL |
| 10 mM | 0.21 mL | 1.05 mL | 2.09 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Hughes Neurochemical evaluation of the novel 5-HT1A receptor partial agonist/serotonin reuptake inhibitor, vilazodone. Eur.J.Pharmacol. 2005 PMID: 15740724
Product Specific Notices for Vilazodone hydrochloride
For research use only
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