VH 032, thiol

Tocris Bioscience, part of Bio-Techne | Catalog # 7861

Functionalized VHL ligand for PROTAC® development
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Key Product Details

Description

Functionalized VHL ligand for PROTAC® development

View all Functionalized E3 Ligand Building Blocks »

Product Description

VH 032, thiol is a functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC® research and development; incorporates an E3 ligase ligand with thiol group for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Usage Guidelines

This product is provided for use in onward chemistry. Suitable solvents can be used.

Product Specifications

Molecular Weight

490.64

Formula

C23H30N4O4S2

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

(2S,4R)-1-((R)-2-Acetamido-3-mercapto-3-methylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide

CAS Number

2098836-54-3

PubChem ID

124201834

InChI Key

MTXNPMAFURZVJC-WSTZPKSXSA-N

SMILES

CC(N[C@@H](C(C)(S)C)C(N1[C@@H](C[C@H](C1)O)C(NCC2=CC=C(C3=C(C)N=CS3)C=C2)=O)=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for VH 032, thiol

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for VH 032, thiol

For research use only

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