VH 032 amide-alkylC9-acid
Tocris Bioscience, part of Bio-Techne | Catalog # 7404
VHL ligand with alkyl linker and terminal acid for onward chemistry
Key Product Details
Description
VHL ligand with alkyl linker and terminal acid for onward chemistry
Alternative Names
(S,R,S)-AHPC-C9-COOH
Product Description
Functionalized von-Hippel-Lindau protein (VHL) ligand for PROTAC® research and development; incorporates an E3 ligase ligand plus an alkylC9 linker with terminal carboxylic acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.
Usage Guidelines
This product is provided for use in onward chemistry. Suitable solvents can be used.Product Specifications
Molecular Weight
628.83
Formula
C33H48N4O6S
Storage
Store at -20°C
Purity
≥95% (HPLC)
Chemical Name
11-(((S)-1-((2S,4R)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-11-oxoundecanoic acid
CAS Number
2172819-78-0
PubChem ID
134184031
InChI Key
MTQZLQCVZFDQOZ-DIIXFEDBSA-N
SMILES
CC1=C(C2=CC=C(C=C2)CNC([C@@H]3C[C@H](CN3C([C@H](C(C)(C)C)NC(CCCCCCCCCC(O)=O)=O)=O)O)=O)SC=N1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
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Product Specific Notices for VH 032 amide-alkylC9-acid
For research use only
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